Vetoryl Capsules for Dogs

Warnings

VETORYL Capsules are not for use in dogs with primary hepatic or renal disease, or in pregnant dogs. Hypoadrenocorticism can develop at any dose of VETORYL Capsules. In some cases, it may take months for adrenal function to return and some dogs never regain adequate adrenal function. All dogs should undergo a thorough history and physical examination before initiation of therapy with VETORYL Capsules.

Precautions

Do not give this medication to pregnant dogs, or dogs with kidney or liver disease.

Experience in foreign markets suggests that when mitotane therapy is stopped, an interval of at least one month should elapse before the introduction of VETORYL Capsules. It is important to wait for both the recurrence of clinical signs consistent with hyperadrenocorticism before treatment with VETORYL Capsules is initiated. Close monitoring of adrenal function is advised, as dogs previously treated with mitotane may be more responsive to the effects of VETORYL Capsules.

Food and Drug Interactions

Human Warnings

Keep out of reach of children. Not for human use. Wash hands after use. Do not empty capsule contents and do not attempt to divide the capsules. Do not handle the capsules if pregnant or if trying to conceive. Trilostane is associated with teratogenic effects and early pregnancy loss in laboratory animals. In the event of accidental ingestion/overdose, seek medical advice immediately and take the labeled container with you.

Possible Side Effects

The most common adverse reactions reported are poor/reduced appetite, vomiting, lethargy/dullness, diarrhea, and weakness. Occasionally, more serious reactions, including severe depression, hemorrhagic diarrhea, collapse, hypoadrenocortical crisis or adrenal necrosis/rupture may occur, and may result in death.

Owners should be advised to discontinue VETORYL Capsules and contact their veterinarian immediately if signs of intolerance such as vomiting, diarrhea, lethargy, poor/reduced appetite, weakness, or collapse are observed.

Contact your veterinarian if you believe your pet is experiencing side effects.

Product Administration

Oral

Product Form

Capsule

Ingredients

Trilostane

Storage

Store at controlled room temperature (59°-86°F)

Manufacturer

Dechra

Prescribing Info/Brochures

• https://www.dechra-us.com/our-products/us/companion-animal/dog/prescription/vetoryl-capsules-trilostane#5-mg